Gentronix News & New Developments

Welcome to the Gentronix Winter 2010 

You’ll be familiar with our GreenScreen HC and HC S9 Screening kits and Services. This E-Mail Alert gives you more information on new published data and where you can find it, announcement of new screening services from Gentronix and details on where you can meet us during the 49th SOT Conference and ToxExpo in Salt Lake City, Utah.

New in vitro Comet screening service
Gentronix expands genotoxicity services

The Comet assay service from Gentronix Ltd offers the opportunity for early identification of compounds likely to exhibit genotoxic liability. This allows prioritization of compounds for development, saving time and money. Use to complement data from the ICH battery or to provide mechanistic insight into earlier results e.g. GreenScreen HC.

Let us know about your in vitro Comet needs by contacting us on [email protected]

New data presented in Mutation Research
Excellent performance of GreenScreen HC against the ECVAM list of Chemicals

 As a follow up to an ECVAM workshop, an expert group compiled a list of recommended compounds for the evaluation of new and improved in vitro genotoxicity tests. 

From this 60 compound study we demonstrated that GreenScreen HC was 90% sensitive, 96% specific and had a concordance of 93%. Read the full paper at:

L.Birrell et al. Mutation Research 695 (2010) 87-95. 

49th SOT Conference and ToxExpo
Salt Lake City, Utah 7-11 March 2010
 

Gentronix are pleased to be exhibiting at ToxExpo at this years SOT meeting in Salt Lake City. Come and visit us at Booth 1919.

We hope to see you there!

We are also co-hosting an exhibitor sponsored session with our predictive toxicology partner Apredica LLC on WEDNESDAY 10th March 12:15-1:15pm during the SOT meeting;

‘Mechanisms of Toxicity and Prediction of Whole-Organ Toxicity: In Vitro Assays and Their Validation-What Can We Predict Early On to Avoid Costly Mistakes Later?

Contact us for more information on this important topic on [email protected] and tell us how we can help you!

Gentronix provides services and solutions to help companies reduce
attrition rates and ensure safer products across a wide range of chemistry driven industries. Our primary focus is on providing more accurate hazard identification for genotoxicity, using GreenScreen HC and complementary assays. See all that we do at www.gentronix.co.uk

Sincerely,

Steve Beasley
Commercial Director
Gentronix Limited